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Participants receiving semaglutide also showed larger reductions in alcohol craving scores and greater improvements on standardized alcohol use questionnaires than those receiving placebo

Weight loss is a secondary effect

Given these overlapping mechanisms, disease-modifying therapies (DMTs) for DM2 have been proposed as potential pharmacotherapies for AD 9

For instance, semaglutide received FDA and EMA approval for cardiovascular risk reduction in patients with obesity in 2024, and Novo Nordisk are also targeting the use of semaglutide in patients with obesity-related heart failure and metabolic associated steatohepatitis (MASH, formerly known as fatty liver disease)